What is Pseudomonas aeruginosa (Pa)?

Pa is a very common bacterium that can cause damage to the lungs in patients with cystic fibrosis (CF).1-4

Pa infects the lungs of nearly everyone with CF at some time during their life1

  • TOBI Podhaler is for people 6 years and older with CF, Pa, and forced expiratory volume in 1 second (FEV1) 25% to 80% predicted and who do not have Burkholderia cepacia.1

In general, the chance of having Pa in the lungs increases with age in patients with CF4

Patients With Cystic Fibrosis and Pseudomonas aeruginosa

Reproduced with permission from the Cystic Fibrosis Foundation.4

What are the effects of Pseudomonas aeruginosa?

Pa can cause lung function to worsen in patients with CF, and is a leading cause of chronic lung infection in patients with CF3

Over time, with Pa in your lungs, you may2,3

  • Develop a cough that doesn't go away

  • Have more mucus in your lungs

  • Feel tightness in your chest

  • Have a hard time catching your breath

If Pa infection is not properly managed, it can continue to damage the lungs and make breathing even more difficult1

Inhaled antibiotics are commonly prescribed by doctors to treat chronic lung infection in patients with CF and Pa. It is important that inhaled antibiotics be taken as prescribed.2,4,5

References: 1. TOBI Podhaler [prescribing information]. East Hanover, NJ: Novartis Pharmaceuticals Corp; 2016. 2. Mogayzel PJ Jr, Naureckas ET, Robinson KA, et al; and Cystic Fibrosis Foundation Pulmonary Clinical Practice Guidelines Committee. Cystic Fibrosis Foundation pulmonary guideline: pharmacologic approaches to prevention and eradication of initial Pseudomonas aeruginosa infection. Ann Am Thorac Soc. 2014;11(10):1640-1650. 3. Lyczak JB, Cannon CL, Pier GB. Lung infections associated with cystic fibrosis. Clin Microbiol Rev. 2002;15(2):194-222. 4. Patient Registry: Annual Data Report 2014. Bethesda, MD: Cystic Fibrosis Foundation; 2015. 5. Antibiotics. Cystic Fibrosis Foundation website. https://www.cff.org/Living-with-CF/Treatments-and-Therapies/Inhaled-Medications/Antibiotics/. Accessed July 19, 2016.